PLoS ONE (Jan 2019)

Association between body mass index and 1-year outcome after acute myocardial infarction.

  • Dae-Won Kim,
  • Sung-Ho Her,
  • Ha Wook Park,
  • Mahn-Won Park,
  • Kiyuk Chang,
  • Wook Sung Chung,
  • Ki Bae Seung,
  • Tae Hoon Ahn,
  • Myung Ho Jeong,
  • Seung-Woon Rha,
  • Hyo-Soo Kim,
  • Hyeon Cheol Gwon,
  • In Whan Seong,
  • Kyung Kuk Hwang,
  • Shung Chull Chae,
  • Kwon-Bae Kim,
  • Young Jo Kim,
  • Kwang Soo Cha,
  • Seok Kyu Oh,
  • Jei Keon Chae,
  • KAMIR-NIH registry investigators

DOI
https://doi.org/10.1371/journal.pone.0217525
Journal volume & issue
Vol. 14, no. 6
p. e0217525

Abstract

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ObjectivesBeneficial effects of overweight and obesity on mortality after acute myocardial infarction (AMI) have been described as "Body Mass Index (BMI) paradox". However, the effects of BMI is still on debate. We analyzed the association between BMI and 1-year clinical outcomes after AMI.MethodsAmong 13,104 AMI patients registered in Korea Acute Myocardial Infarction Registry-National Institute of Health (KAMIR-NIH) between November 2011 and December 2015, 10,568 patients who eligible for this study were classified into 3 groups according to BMI (Group 1; ResultsOver the median follow-up of 12 months, the event of primary end point occurred more frequently in the Group 1 patients than in the Group 3 patients (primary endpoint: adjusted hazard ratio [aHR], 1.537; 95% confidence interval [CI] 1.177 to 2.007, p = 0.002). Especially, cardiac death played a major role in this effect (aHR, 1.548; 95% confidence interval [CI] 1.128 to 2.124, p = 0.007).ConclusionsHigher BMI appeared to be good prognostic factor on 1-year all cause death after AMI. This result suggests that higher BMI or obesity might confer a protective advantage over the life-quality after AMI.