Nature Communications (Nov 2020)
Genome-enabled discovery of anthraquinone biosynthesis in Senna tora
- Sang-Ho Kang,
- Ramesh Prasad Pandey,
- Chang-Muk Lee,
- Joon-Soo Sim,
- Jin-Tae Jeong,
- Beom-Soon Choi,
- Myunghee Jung,
- Daniel Ginzburg,
- Kangmei Zhao,
- So Youn Won,
- Tae-Jin Oh,
- Yeisoo Yu,
- Nam-Hoon Kim,
- Ok Ran Lee,
- Tae-Ho Lee,
- Puspalata Bashyal,
- Tae-Su Kim,
- Woo-Haeng Lee,
- Charles Hawkins,
- Chang-Kug Kim,
- Jung Sun Kim,
- Byoung Ohg Ahn,
- Seung Yon Rhee,
- Jae Kyung Sohng
Affiliations
- Sang-Ho Kang
- Genomics Division, National Institute of Agricultural Sciences, RDA
- Ramesh Prasad Pandey
- Department of Pharmaceutical Engineering and Biotechnology, Sun Moon University
- Chang-Muk Lee
- Metabolic Engineering Division, National Institute of Agricultural Sciences, RDA
- Joon-Soo Sim
- Metabolic Engineering Division, National Institute of Agricultural Sciences, RDA
- Jin-Tae Jeong
- Department of Herbal Crop Research, National Institute of Horticultural and Herbal Science, RDA
- Beom-Soon Choi
- Phyzen Genomics Institute
- Myunghee Jung
- Department of Forest Science, College of Agriculture and Life Science, Seoul National University
- Daniel Ginzburg
- Department of Plant Biology, Carnegie Institution for Science
- Kangmei Zhao
- Department of Plant Biology, Carnegie Institution for Science
- So Youn Won
- Genomics Division, National Institute of Agricultural Sciences, RDA
- Tae-Jin Oh
- Department of Pharmaceutical Engineering and Biotechnology, Sun Moon University
- Yeisoo Yu
- Phyzen Genomics Institute
- Nam-Hoon Kim
- Phyzen Genomics Institute
- Ok Ran Lee
- Department of Applied Plant Science, College of Agriculture and Life Science, Chonnam National University
- Tae-Ho Lee
- Genomics Division, National Institute of Agricultural Sciences, RDA
- Puspalata Bashyal
- Department of Pharmaceutical Engineering and Biotechnology, Sun Moon University
- Tae-Su Kim
- Department of Pharmaceutical Engineering and Biotechnology, Sun Moon University
- Woo-Haeng Lee
- Department of Pharmaceutical Engineering and Biotechnology, Sun Moon University
- Charles Hawkins
- Department of Plant Biology, Carnegie Institution for Science
- Chang-Kug Kim
- Genomics Division, National Institute of Agricultural Sciences, RDA
- Jung Sun Kim
- Genomics Division, National Institute of Agricultural Sciences, RDA
- Byoung Ohg Ahn
- Genomics Division, National Institute of Agricultural Sciences, RDA
- Seung Yon Rhee
- Department of Plant Biology, Carnegie Institution for Science
- Jae Kyung Sohng
- Department of Pharmaceutical Engineering and Biotechnology, Sun Moon University
- DOI
- https://doi.org/10.1038/s41467-020-19681-1
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 11
Abstract
Anthraquinones are aromatic polyketides and have been used for treating various diseases, but the biosynthetic pathway is unclear. Here, the authors assemble the genome of an anthraquinone-producing medicinal plant Senna tora and show the evidences that CHS-like genes may be involved in anthraquinone biosynthesis.
