Nature Communications (Nov 2020)

Genome-enabled discovery of anthraquinone biosynthesis in Senna tora

  • Sang-Ho Kang,
  • Ramesh Prasad Pandey,
  • Chang-Muk Lee,
  • Joon-Soo Sim,
  • Jin-Tae Jeong,
  • Beom-Soon Choi,
  • Myunghee Jung,
  • Daniel Ginzburg,
  • Kangmei Zhao,
  • So Youn Won,
  • Tae-Jin Oh,
  • Yeisoo Yu,
  • Nam-Hoon Kim,
  • Ok Ran Lee,
  • Tae-Ho Lee,
  • Puspalata Bashyal,
  • Tae-Su Kim,
  • Woo-Haeng Lee,
  • Charles Hawkins,
  • Chang-Kug Kim,
  • Jung Sun Kim,
  • Byoung Ohg Ahn,
  • Seung Yon Rhee,
  • Jae Kyung Sohng

DOI
https://doi.org/10.1038/s41467-020-19681-1
Journal volume & issue
Vol. 11, no. 1
pp. 1 – 11

Abstract

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Anthraquinones are aromatic polyketides and have been used for treating various diseases, but the biosynthetic pathway is unclear. Here, the authors assemble the genome of an anthraquinone-producing medicinal plant Senna tora and show the evidences that CHS-like genes may be involved in anthraquinone biosynthesis.