25-Hydroxyvitamin D Serum Levels Linked to Single-Nucleotide Polymorphisms (SNPs) (rs2228570, rs2282679, rs10741657) in Sports Performance in CrossFit^® Elite Athletes

Abstract

Vitamin D substantially influences sports performance and post-exercise recovery because it offers anti-inflammatory, antioxidant and cellular protective properties. However, deficient levels of 25-hydroxyvitamin D 25(OH)D (25(OH)D) (® practitioners. Knowing these relationships could be instrumental for personalized vitamin D supplementation and training strategies. Using a standardized commercial enzyme-linked immunosorbent assay procedure, the concentrations of 25(OH)D were determined and the genotyping procedures for each SNPs were carried out using specific assays with the KASpar® test. The 25(OH)DA performance level in grades was established based on the CrossFit® Total score (sum in kilograms of one Repetition Max Squat, Press and Deadlift). Significant differences (p p ® practitioners. These results could highlight that the evaluation of genetic factors is key to designing a vitamin D supplementation strategy to improve sports performance.

Keywords

• sports performance
• 25-OH vitamin D
• SNPs
• genetics
• elite athletes