Regression of an asymptomatic choroidal metasta- sis from breast carcinoma following letrozole therapy*

Abstract

Background: Uveal metastases are commonly of breast origin, typically affecting the posterior choroid. Treatment of such uveal tumours can lead to significant ocular side effects. Methods: We present the clinical and optical coherence tomography findings of a patient with an asymptomatic choroidal metastases. Results: A 62-year-old lady presented with an asymptomatic uniocular choroidal metastases from breast origin. She was being treated with letrozole, a nonsteroidal aromatose inhibitor, for known pleural metastases. The choroidal lesion was inactive at presentation to our clinic and required no further treatment. Conclusion: The use of letrozole can lead to choroidal metastasis regression.

Keywords

• Choroidal metastasis
• letrozole
• breast carcinoma
• aromatase inhibitors