Formose reaction controlled by boronic acid compounds

Abstract

Formose reactions were carried out in the presence of low molecular weight and macromolecular boronic acid compounds, i.e., sodium phenylboronate (SPB) and a copolymer of sodium 4-vinylphenylboronate with sodium 4-styrenesulfonate (pVPB/NaSS), respectively. The boronic acid compounds provided different selectivities; sugars of a small carbon number were formed favorably in the presence of SPB, whereas sugar alcohols of a larger carbon number were formed preferably in the presence of pVPB/NaSS.

Keywords

• boronic acid compounds
• formose reaction
• sodium phenylboronate
• sodium 4-vinylphenylboronate/sodium 4-styrenesulfonate copolymer
• sugar alcohols
• sugars