Photoacoustic identification of blood vessel deformation under pressure
Xiaoman Zhang,
Cuncheng Weng,
Shulian Wu,
Jianyong Cai,
Huaqin Wu,
Zhifang Li,
Lili Zhu,
Hui Li
Affiliations
Xiaoman Zhang
Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Provincial Key Laboratory of Photonics Technology, Fujian Provincial Engineering Technology Research Center for OptoElectronic Sensing Applications College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou 350007, P.R. China
Cuncheng Weng
Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Provincial Key Laboratory of Photonics Technology, Fujian Provincial Engineering Technology Research Center for OptoElectronic Sensing Applications College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou 350007, P.R. China
Shulian Wu
Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Provincial Key Laboratory of Photonics Technology, Fujian Provincial Engineering Technology Research Center for OptoElectronic Sensing Applications College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou 350007, P.R. China
Jianyong Cai
Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Provincial Key Laboratory of Photonics Technology, Fujian Provincial Engineering Technology Research Center for OptoElectronic Sensing Applications College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou 350007, P.R. China
Huaqin Wu
Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Provincial Key Laboratory of Photonics Technology, Fujian Provincial Engineering Technology Research Center for OptoElectronic Sensing Applications College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou 350007, P.R. China
Zhifang Li
Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Provincial Key Laboratory of Photonics Technology, Fujian Provincial Engineering Technology Research Center for OptoElectronic Sensing Applications College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou 350007, P.R. China
Lili Zhu
Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Provincial Key Laboratory of Photonics Technology, Fujian Provincial Engineering Technology Research Center for OptoElectronic Sensing Applications College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou 350007, P.R. China
Hui Li
Key Laboratory of OptoElectronic Science and Technology for Medicine of Ministry of Education, Fujian Provincial Key Laboratory of Photonics Technology, Fujian Provincial Engineering Technology Research Center for OptoElectronic Sensing Applications College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou 350007, P.R. China
In this work we demonstrate a photoacoustic system which can identify the deformation of blood vessels under external pressure. Using photoacoustic imaging method, the vessel internal diameter can be derived from the peak-to-peak time interval of the laser (532nm) induced the photoacoustic signals. Comparisons with the actual vessel inter diameter show that the relative deviation is less than 4%, which proves the validity of this method. Interestingly, we find that the axial diameter of the blood vessel and the blood volume increase monotonously with increasing transient pressure, and the laser-induced photoacoustic signal is mainly contributed by the blood inside the vessel. Our results suggest a new way for continuous monitoring of the deformation of blood vessels under pressure.
