Sandostatin i Sandostatin LAR pri metabolicheskikh, neyroendokrinnykh i onkologicheskikh zabolevaniyakh

Abstract

Octreotide is a synthetic analog of hypothalamic hormone somatostatin. This neuropeptide is widely distributed in humans and animals in central nervous system and periphery, which defines its potential regulatory functions. In 1987 the first registration was received for octreotide preparation, Sandostatin, for treatment of acromegaly and carcinoid tumors. In 1997 a long lasting form of octreotide appeared - Sandostatin LAR. At the present time both preparations have found their use in multiple areas of medicine for treatment of different metabolic, neuroendocrine and oncologic diseases.

Keywords

• somatostatin
• octreotide
• sandostatin
• sandostatin lar
• acromegaly
• neuroendocrine tumors
• obesity