Metabolic signatures in human follicular fluid identify lysophosphatidylcholine as a predictor of follicular development

Jihong Yang; Yangbai Li; Suying Li; Yan Zhang; Ruizhi Feng; Rui Huang; Minjian Chen; Yun Qian

doi:10.1038/s42003-022-03710-4

Communications Biology (Jul 2022)

Metabolic signatures in human follicular fluid identify lysophosphatidylcholine as a predictor of follicular development

Jihong Yang,
Yangbai Li,
Suying Li,
Yan Zhang,
Ruizhi Feng,
Rui Huang,
Minjian Chen,
Yun Qian

Affiliations

Jihong Yang: Reproductive Medical Center of Second Affiliated Hospital of Nanjing Medical University
Yangbai Li: Reproductive Medical Center of Second Affiliated Hospital of Nanjing Medical University
Suying Li: Reproductive Medical Center of Second Affiliated Hospital of Nanjing Medical University
Yan Zhang: Reproductive Medical Center of Second Affiliated Hospital of Nanjing Medical University
Ruizhi Feng: State Key Laboratory of Reproductive Medicine, Nanjing Medical University
Rui Huang: Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University
Minjian Chen: Key Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University
Yun Qian: Reproductive Medical Center of Second Affiliated Hospital of Nanjing Medical University

DOI: https://doi.org/10.1038/s42003-022-03710-4
Journal volume & issue: Vol. 5, no. 1
pp. 1 – 11

Abstract

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A two-stage metabolomic analysis for human follicular fluid characteristics and predictors of follicular development yields metabolic signatures and proposes lysophosphatidylcholine (LPC) as a biomarker for follicular development.

Published in Communications Biology

ISSN: 2399-3642 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science: Biology (General)
Website: https://www.nature.com/commsbio/

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