Communications Medicine (Jan 2023)
Biomedical consequences of elevated cholesterol-containing lipoproteins and apolipoproteins on cardiovascular and non-cardiovascular outcomes
- Amand F. Schmidt,
- Roshni Joshi,
- Maria Gordillo-Marañón,
- Fotios Drenos,
- Pimphen Charoen,
- Claudia Giambartolomei,
- Joshua C. Bis,
- Tom R. Gaunt,
- Alun D. Hughes,
- Deborah A. Lawlor,
- Andrew Wong,
- Jackie F. Price,
- Nishi Chaturvedi,
- Goya Wannamethee,
- Nora Franceschini,
- Mika Kivimaki,
- Aroon D. Hingorani,
- Chris Finan
Affiliations
- Amand F. Schmidt
- Institute of Cardiovascular Science, Faculty of Population Health, University College London
- Roshni Joshi
- Institute of Cardiovascular Science, Faculty of Population Health, University College London
- Maria Gordillo-Marañón
- Institute of Cardiovascular Science, Faculty of Population Health, University College London
- Fotios Drenos
- Institute of Cardiovascular Science, Faculty of Population Health, University College London
- Pimphen Charoen
- Institute of Cardiovascular Science, Faculty of Population Health, University College London
- Claudia Giambartolomei
- Istituto Italiano di Tecnologia, Non-coding RNAs and RNA-based Therapeutics
- Joshua C. Bis
- Cardiovascular Health Research Unit, Department of Medicine, University of Washington
- Tom R. Gaunt
- MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol
- Alun D. Hughes
- Institute of Cardiovascular Science, Faculty of Population Health, University College London
- Deborah A. Lawlor
- MRC Integrative Epidemiology Unit, Bristol Medical School, University of Bristol
- Andrew Wong
- MRC Unit for Lifelong Health and Ageing, University College London
- Jackie F. Price
- Usher Institute, University of Edinburgh
- Nishi Chaturvedi
- Institute of Cardiovascular Science, Faculty of Population Health, University College London
- Goya Wannamethee
- Primary Care and Population Health, University College London
- Nora Franceschini
- Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina
- Mika Kivimaki
- Department of Mental Health of Older People, Division of Brain Sciences, University College London
- Aroon D. Hingorani
- Institute of Cardiovascular Science, Faculty of Population Health, University College London
- Chris Finan
- Institute of Cardiovascular Science, Faculty of Population Health, University College London
- DOI
- https://doi.org/10.1038/s43856-022-00234-0
- Journal volume & issue
-
Vol. 3,
no. 1
pp. 1 – 10
Abstract
Schmidt et al. evaluate the effects of elevated circulating concentrations of cholesterol-containing lipoproteins and apolipoproteins. Effects are seen on measures of atherosclerosis, blood pressure, c-reactive protein, coronary heart disease, heart failure, Alzheimer’s disease, type 2 diabetes and inflammatory bowel disease.
