Construction of azaheterocycles via Pd-catalyzed migratory cycloannulation reaction of unactivated alkenes

Jin-Ping Wang; Shuo Song; Yichen Wu; Peng Wang

doi:10.1038/s41467-022-32726-x

Nature Communications (Aug 2022)

Construction of azaheterocycles via Pd-catalyzed migratory cycloannulation reaction of unactivated alkenes

Jin-Ping Wang,
Shuo Song,
Yichen Wu,
Peng Wang

Affiliations

Jin-Ping Wang: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences
Shuo Song: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences
Yichen Wu: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences
Peng Wang: State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, University of Chinese Academy of Sciences

DOI: https://doi.org/10.1038/s41467-022-32726-x
Journal volume & issue: Vol. 13, no. 1
pp. 1 – 10

Abstract

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Azahetereocycles represent promising scaffolds in drug discovery. Here, the authors report a Pd-catalyzed migratory cycloannulation strategy for efficient construction of a wide range of azahetereocycles from unactivated aliphatic alkenes.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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