PLoS ONE (Jan 2015)

Live birth and cumulative live birth rates in expected poor ovarian responders defined by the Bologna criteria following IVF/ICSI treatment.

  • Joyce Chai,
  • Vivian Chi-Yan Lee,
  • Tracy Wing-Yee Yeung,
  • Hang Wun Raymond Li,
  • Pak-Chung Ho,
  • Ernest Hung-Yu Ng

DOI
https://doi.org/10.1371/journal.pone.0119149
Journal volume & issue
Vol. 10, no. 3
p. e0119149

Abstract

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To determine the live birth and cumulative live birth rates of expected poor ovarian responders according to the Bologna criteria and to compare their outcomes with those of expected normal responders.Retrospective analysis.University infertility clinic.A total of 1,152 subfertile women undergoing their first in vitro fertilization (IVF) cycle.Women were classified into 4 groups according to the Bologna criteria for comparison.Live birth and cumulative live birth rates.Women with expected poor response (POR) had the lowest live birth rate than the other 3 groups (23.8%, p = 0.031). Cumulative live birth rates were significantly lower in those with expected POR than those with expected normal ovarian response (NOR) (35.8% vs 62.8%, p3 oocytes, p = 0.006) whereas the live birth rates in fresh cycle did not differ (17.8% vs 30.9%, p = 0.108).Women who were expected POR according to the Bologna criteria had lower live birth and cumulative live birth than expected NOR but they still can achieve reasonable treatment outcomes and IVF treatment should not be precluded.