Communications Biology (Oct 2022)

The purine metabolite inosine monophosphate accelerates myelopoiesis and acute pancreatitis progression

  • Xiao-Min Luo,
  • Sin Man Lam,
  • Yuan Dong,
  • Xiao-Juan Ma,
  • Cen Yan,
  • Yue-Jie Zhang,
  • Yu Cao,
  • Li Su,
  • Guotao Lu,
  • Jin-Kui Yang,
  • Guanghou Shui,
  • Ying-Mei Feng

DOI
https://doi.org/10.1038/s42003-022-04041-0
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 14

Abstract

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Metabolomics analysis reveals that inosine monophosphate, a purine metabolite, promotes myelopoiesis and contributes to severe acute pancreatitis in db/db mice.