Nature Communications (Sep 2022)

Structure and activity of particulate methane monooxygenase arrays in methanotrophs

  • Yanan Zhu,
  • Christopher W. Koo,
  • C. Keith Cassidy,
  • Matthew C. Spink,
  • Tao Ni,
  • Laura C. Zanetti-Domingues,
  • Benji Bateman,
  • Marisa L. Martin-Fernandez,
  • Juan Shen,
  • Yuewen Sheng,
  • Yun Song,
  • Zhengyi Yang,
  • Amy C. Rosenzweig,
  • Peijun Zhang

DOI
https://doi.org/10.1038/s41467-022-32752-9
Journal volume & issue
Vol. 13, no. 1
pp. 1 – 10

Abstract

Read online

Particulate methane monooxygenase (pMMO) is the main enzyme used by methanotrophs. Here, the authors determined the native structure of pMMO by cryo-electron tomography, revealing lipid-stabilized features and a higher-order hexagonal array arrangement in intact cells.