Endocrinology, Diabetes & Metabolism Case Reports (Mar 2022)

A 17-year-old boy with lymphocytic infundibuloneurohypophysitis who developed non-alcoholic steatohepatitis effectively treated with growth hormone

  • Hidekuni Takahashi,
  • Shigeo Nishimata,
  • Atsushi Kumada,
  • Gaku Yamanaka,
  • Yasuyo Kashiwagi,
  • Hisashi Kawashima

DOI
https://doi.org/10.1530/EDM-21-0148
Journal volume & issue
Vol. 1, no. 1
pp. 1 – 5

Abstract

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We encountered a case of childhood-onset lymphocytic infundibuloneurohypophysitis, based on the MRI and endocrinological findings, with decreased function of the anterior and posterior lobes of the pituitary. Three years after the diagnosis, the patient developed non-alcoholic steatohepatitis (NASH), which was effectively treated by growth hormone (GH) supplementation. The present case demonstrated that NASH can be effectively treated by short-term GH supplementation, even in late childhood.