Molecules (Jan 2024)

The Extraction, Determination, and Bioactivity of Curcumenol: A Comprehensive Review

  • Jie Li,
  • Yitian Sun,
  • Guohua Li,
  • Chunsong Cheng,
  • Xinbing Sui,
  • Qibiao Wu

DOI
https://doi.org/10.3390/molecules29030656
Journal volume & issue
Vol. 29, no. 3
p. 656

Abstract

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Curcuma wenyujin is a member of the Curcuma zedoaria (zedoary, Zingiberaceae) family, which has a long history in traditional Chinese medicine (TCM) due to its abundant biologically active constituents. Curcumenol, a component of Curcuma wenyujin, has several biological activities. At present, despite different pharmacological activities being reported, the clinical usage of curcumenol remains under investigation. To further determine the characteristics of curcumenol, the extraction, determination, and bioactivity of the compound are summarized in this review. Existing research has reported that curcumenol exerts different pharmacological effects in regard to a variety of diseases, including anti-inflammatory, anti-oxidant, anti-bactericidal, anti-diabetic, and anti-cancer activity, and also ameliorates osteoporosis. This review of curcumenol provides a theoretical basis for further research and clinical applications.

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