Effectiveness of Meningococcal B Vaccine against Endemic Hypervirulent Neisseria meningitidis W Strain, England

Abstract

Serum samples from children immunized with a meningococcal serogroup B vaccine demonstrated potent serum bactericidal antibody activity against the hypervirulent Neisseria meningitidis serogroup W strain circulating in England. The recent introduction of this vaccine into the United Kingdom national immunization program should also help protect infants against this endemic strain.

Keywords

• Neisseria meningitidis, meningococcal W disease
• ST-11 clonal complex
• prevention
• meningococci, serum bactericidal antibody (SBA) activity, immunization, endemic, meningitis, Bexsero, Menveo, England
• Neisseria meningitidis
• meningococcal W disease