Bortezomib-induced neurotoxicity in human neurons is the consequence of nicotinamide adenine dinucleotide depletion

• Andrew R. Snavely,
• Keungjung Heo,
• Veselina Petrova,
• Tammy Szu-Yu Ho,
• Xuan Huang,
• Crystal Hermawan,
• Ruth Kagan,
• Tao Deng,
• Ilyas Singeç,
• Long Chen,
• Lee B. Barret,
• Clifford J. Woolf

Affiliations

Andrew R. Snavely

F.M. Kirby Neurobiology Center, Program in Neurobiology, Boston Children's Hospital, Boston, MA 02115, USA

Keungjung Heo

F.M. Kirby Neurobiology Center, Program in Neurobiology, Boston Children's Hospital, Boston, MA 02115, USA

Veselina Petrova

F.M. Kirby Neurobiology Center, Program in Neurobiology, Boston Children's Hospital, Boston, MA 02115, USA

Tammy Szu-Yu Ho

F.M. Kirby Neurobiology Center, Program in Neurobiology, Boston Children's Hospital, Boston, MA 02115, USA

Xuan Huang

F.M. Kirby Neurobiology Center, Program in Neurobiology, Boston Children's Hospital, Boston, MA 02115, USA

Crystal Hermawan

F.M. Kirby Neurobiology Center, Program in Neurobiology, Boston Children's Hospital, Boston, MA 02115, USA

Ruth Kagan

Department of Neurobiology, Harvard Medical School, Boston, MA 02115, USA

Tao Deng

National Center for Advancing Translational Sciences (NCATS), Division of Preclinical Innovation, Stem Cell Translation Laboratory (SCTL), National Institutes of Health (NIH), Rockville, MD 20850, USA

Ilyas Singeç

National Center for Advancing Translational Sciences (NCATS), Division of Preclinical Innovation, Stem Cell Translation Laboratory (SCTL), National Institutes of Health (NIH), Rockville, MD 20850, USA

Long Chen

F.M. Kirby Neurobiology Center, Program in Neurobiology, Boston Children's Hospital, Boston, MA 02115, USA

Lee B. Barret

F.M. Kirby Neurobiology Center, Program in Neurobiology, Boston Children's Hospital, Boston, MA 02115, USA

Clifford J. Woolf

F.M. Kirby Neurobiology Center, Program in Neurobiology, Boston Children's Hospital, Boston, MA 02115, USA