Infection and Drug Resistance (Apr 2022)
Acute Post-Cataract Endophthalmitis Due to Phialemoniopsis curvata: A Rare Case Report
Abstract
Mengli Tang,1,* Jun Li,1,2,* Fengjun Xia,1 Changhang Min,1 Zhaojun Liu,1 Yongmei Hu,1,2 Haichen Wang,1,2 Heping Xu,3 Mingxiang Zou1,2 1Department of Clinical Laboratory, Xiangya Hospital, Central South University, Changsha, Hunan, People’s Republic of China; 2National Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South University, Changsha, Hunan, People’s Republic of China; 3Department of Clinical Laboratory, the First Affiliated Hospital of Xiamen University, Xiamen, Fujian, People’s Republic of China*These authors contributed equally to this workCorrespondence: Mingxiang Zou, Department of Clinical Laboratory, Xiangya Hospital, Central South University, No. 87, Xiangya Road, Changsha, 410008, Hunan, People’s Republic of China, Tel +86 13907496278, Email [email protected]: Phialemonium species are a class of opportunistic pathogenic fungi widely present in the environment that cause invasive diseases in hosts with normal or weak immune functions. Common infections include peritonitis, endocarditis, osteomyelitis, and skin infections of wounds after burns, whereas endophthalmitis is rarely reported. Here, we report acute post-cataract endophthalmitis caused by Phialemoniopsis curvata in China. The isolated pathogen was identified using microscopy, culture, and sequencing. After vitrectomy, intraocular lens removal surgery, voriconazole injection, and topical voriconazole treatment, the patient’s symptoms were alleviated.Keywords: Phialemoniopsis curvata, fungal endophthalmitis, cataract surgery, voriconazole
