Korean Journal of Transplantation (Jun 2021)

Severe anorexia and weight loss induced by tacrolimus in kidney transplant recipients

  • Hong Pil Hwang,
  • Hee Chul Yu,
  • Byeoung Hoon Chung,
  • Kyung Pyo Kang,
  • Won Kim,
  • Sung Kwang Park,
  • Sik Lee

DOI
https://doi.org/10.4285/kjt.20.0058
Journal volume & issue
Vol. 35, no. 2
pp. 108 – 111

Abstract

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Common neuropsychiatric complications of tacrolimus include tremors, fatigue, headache, sleep disorders, paranoid reactions, and anxiety. Other, more serious complications include encephalopathy, convulsions, confusion, and coma. To our knowledge, however, severe weight loss by anorexia has not been reported as a neuropsychiatric adverse effect of tacrolimus given to adult kidney transplant recipients. In this article we present two cases of severe anorexia and weight loss associated with tacrolimus that appeared to reverse with cyclosporine.

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