The association between plasma concentration of pigment epithelium-derived factor and diabetic retinopathy

Abstract

Diabetic retinopathy (DRP) is one of the most common microvascular complications of diabetes. The pigment epithelium-derived factor (PEDF) is a protein that is one of the most potent angiogenesis inhibitors. The effect of blood PEDF concentration on DRP formation remains unclear. The present study aimed to determine whether the plasma concentration of PEDF is effective on the appearance of DRP.

Keywords

• diabetic retinopathy
• pigment epithelium-derived factor
• diabetic complications
• diabetes mellitus