Deoxyfluorination of alcohols with 3,3-difluoro-1,2-diarylcyclopropenes

Abstract

Fluorination of organic molecules can dramatically change the properties and is commonly used for the synthesis of bioactive molecules. Here, the authors report the deoxyfluorination of alcohols and the selective monofluorination of diols using bench stable, tunable difluorocyclopropene reagents.