Clinical, Cosmetic and Investigational Dermatology (Sep 2022)
Signet-Ring Cutaneous Metastasis Presenting with Huge Bunches of Grapes
Abstract
Zhenyu Hao *, Yongqiong Deng *, Yuanmin He, Xia Xiong Department of Dermatology STD, The Affiliated Hospital of Southwest Medical University, Luzhou, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yongqiong Deng, Department of Dermatology, The Affiliated Hospital of Southwest Medical University, No. 25, Taiping Street, Luzhou, 646000, People’s Republic of China, Tel +8613679670608, Email [email protected]: Signet-ring cell (SRC) is a histologic type in which cells show unique features under the microscope. We mainly found signet-ring cells (SRCs) in gastrointestinal and breast tumors. Cutaneous metastasis from internal carcinomas was an uncommon presentation. The cases of signet-ring cell carcinoma (SRCC) metastasis to the skin were rarely reported. Cutaneous metastasis indicated a poor prognosis for a patient. Here, we report a female who had huge grape-like nodules arising from gastrointestinal SRCC in her trunk and thigh.Keywords: signet-ring cutaneous metastasis, SRCC, signet-ring cell carcinoma, unknown primary tumors, gastrointestinal tumors
