Oncology Reviews (Jun 2011)
Oncology is changing: the challenge of effectively assessing response within clinical trials in low-grade gliomas
Abstract
The current WHO classification of primary central nervous system (CNS) tumors recognizes four separate tumor grades (I–IV), which can be grouped into low-grade (I and II) or high-grade (III and IV), depending on the absence or presence of high-grade histopathological features, such as microvascular proliferation and necrosis...
