PLoS ONE (Jan 2014)

Treatment results in the different surgery of intradural extramedullary tumor of 122 cases.

  • Shaohui Zong,
  • Gaofeng Zeng,
  • Li Du,
  • Ye Fang,
  • Taihang Gao,
  • Jingmin Zhao

DOI
https://doi.org/10.1371/journal.pone.0111495
Journal volume & issue
Vol. 9, no. 11
p. e111495

Abstract

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STUDY DESIGN: A retrospective study of intradural extramedullary tumor. OBJECTIVE: To compare the treatment results in the different surgeries of spinal intradural extramedullary tumor. METHODS: The study retrospectively reviewed 122 patients. The minimally invasive surgery (MIS) group was divided into Group A (hemilaminectomy + tumor microscopic excision) and Group B (laminectomy + tumor microscopic excision + pedicle screw fixation). Meanwhile, the non-MIS group was divided into Group C (hemilaminectomy + tumor excision), Group D (laminectomy + tumor excision), and Group E (laminectomy + tumor excision + pedicle screw fixation). In order to study postoperative spinal stability, we simultaneously divided all of the subjects into three categories, namely Group HE: hemilaminectomy + tumor excision; Group LE: laminectomy + tumor excision; and Group LEPSF: laminectomy + tumor excision + pedicle screw fixation. RESULTS: The MIS group exhibited fewer postoperative complications (p<0.05), better short-term clinical efficacy (p<0.05) and less non-surgical cost (p<0.05) than in non-MIS group. The rate of postoperative spinal instability in hemilaminectomy was lower than in laminectomy in a single spinal segment (p<0.05). The rate of postoperative spinal instability in laminectomy + pedicle screw fixation was lower than in hemilaminectomy and laminectomy in two or more spinal segments (p<0.05). CONCLUSION: In the case of appropriate surgical indications, minimally invasive surgery for intradural extramedullary tumor is a useful method that can successfully produce good clinical results and reduce non-surgical cost. In addition, pedicle screw fixation helps avoid spinal postoperative instability.