Communications Medicine (Feb 2023)

MRI-based deep learning can discriminate between temporal lobe epilepsy, Alzheimer’s disease, and healthy controls

  • Allen J. Chang,
  • Rebecca Roth,
  • Eleni Bougioukli,
  • Theodor Ruber,
  • Simon S. Keller,
  • Daniel L. Drane,
  • Robert E. Gross,
  • James Welsh,
  • Anees Abrol,
  • Vince Calhoun,
  • Ioannis Karakis,
  • Erik Kaestner,
  • Bernd Weber,
  • Carrie McDonald,
  • Ezequiel Gleichgerrcht,
  • Leonardo Bonilha,
  • Alzheimer’s Disease Neuroimaging Initiative

DOI
https://doi.org/10.1038/s43856-023-00262-4
Journal volume & issue
Vol. 3, no. 1
pp. 1 – 11

Abstract

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Chang et al. classify people with Temporal Lobe Epilepsy (TLE), Alzheimer’s disease and healthy controls using a convolutional neural network algorithm applied to magnetic resonance imaging (MRI) scans. People with TLE can be distinguished, including those without easily identifiable TLE-associated MRI features.