Interaction among long non‐coding RNA, micro‐RNA and mRNA in glioma

Abstract

With the rapid development and wide application of gene sequencing, biotechnology, and informatics about cancer, it has been found that the main causes of malignant gliomas occurrence not only consist of abnormal mutations of protein‐coding genes but also abnormal expressions of non‐coding RNA (ncRNA). In this review, we summarize the interaction and mechanism between lncRNA‐miRNA‐mRNA and gliomas in occurrence, development, aggression, and migration in depth.

Keywords

• lncRNA
• miRNA
• ceRNA
• GBM