Malonates in Cyclocondensation Reactions

Abstract

The use of malonates such as diethyl malonates 9, (chlorocarbonyl)ketenes 15 and bis(2,4,6-trichlorophenyl) malonates 18 as reagents for cyclocondensation with 1,3-dinucleophiles to give six-membered heterocycles is described. Further attempts to use malonates such as bis(trimethylsilyl) malonates 19 and bis(carbamimidoyl) malonates 29 as new cyclocondensation agents are described .

Keywords

• ethyl malonates
• (chlorocarbonyl)ketenes
• bis(2
• 4
• 6-trichlorophenyl) malonates
• bis(trimethylsilyl) malonates
• sixmembered heterocycles