Biological isolation and characterization of Catharanthus roseus (L.) G. Don methanolic leaves extracts and their assessment for antimicrobial, cytotoxic, and apoptotic activities

Abstract

Highlights • The methanolic leaf extracts of the Catharanthus roseus plants contain secondary metabolites. • CrPLE extracts showed antimicrobial and anticancer activities. • The use of Catharanthus roseus plants as a “natural herbal resource” in the pharmaceutical and pharmacological industry has been validated and further expanded.

Keywords

• Antibacterial activity
• Anticancer activity
• Apoptosis
• Methanolic leaf extracts
• MDA-MB-231 cell lines