Dataset on the activation of Müller cells through macrophages upon hypoxia in the retina
Christina Nürnberg,
Norbert Kociok,
Claudia Brockmann,
Timo Lischke,
Sergio Crespo-Garcia,
Nadine Reichhart,
Susanne Wolf,
Ria Baumgrass,
Sabine A. Eming,
Sandra Beer-Hammer,
Antonia M. Joussen
Affiliations
Christina Nürnberg
Department of Ophthalmology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany; Corresponding author.
Norbert Kociok
Department of Ophthalmology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Claudia Brockmann
Department of Ophthalmology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Timo Lischke
German Rheumatism Research Center Berlin, a Leibniz Institute, Berlin, Germany
Sergio Crespo-Garcia
Department of Ophthalmology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Nadine Reichhart
Department of Ophthalmology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
Susanne Wolf
Department of Cellular Neuroscience, Max Delbrück Center in the Helmholtz Society, Berlin, Germany
Ria Baumgrass
German Rheumatism Research Center Berlin, a Leibniz Institute, Berlin, Germany
Sabine A. Eming
Department of Dermatology, University of Cologne, Germany
Sandra Beer-Hammer
Department of Pharmacology and Experimental Therapy and Interfaculty Center of Pharmacogenomics and Drug Research, University of Tübingen, Germany
Antonia M. Joussen
Department of Ophthalmology, Charité – Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany
The dataset presented in this article complements the article entitled “Myeloid cells contribute indirectly to VEGF expression upon hypoxia via activation of Müller cells” (C. Nürnberg, N. Kociok, C. Brockmann, T. Lischke, S. Crespo-Garcia, N. Reichhart, S. Wolf, R. Baumgrass, S.A. Eming, S. Beer-Hammer, and A.M. Joussen). This complementary dataset provides further insight into the experimental validation of the VEGFfl/fl LysMCre (here named VEGFmcko) knockout model used in the main article through genomic and quantitative Real-Time PCR in various murine tissues as well as additional flow cytometry data and immunohistochemical stainings. By providing these data, we aim to enable researcher to reproduce and critically analyze our data.
