PI3K/AKT Pathway and Brain Malformations

Abstract

Investigators from Seattle Children's Research Institute, University of Washington, and collaborating institutions sought to evaluate 10 genes in the PI3K/AKT pathway as it relates epileptogenic brain malformations in patients with megalencephaly, hemimegalencephaly, and focal cortical dysplasia.

Keywords

• pi3k/akt mutations
• cortical dysplasia
• megalencephaly