Respiratory Medicine Case Reports (Jan 2017)

Right ventricular reverse remodelling in Idiopathic Pulmonary Arterial Hypertension diagnosed during pregnancy: Is it possible?

  • Giuseppe Paciocco,
  • Andrea Lombi,
  • Antonella Vincenzi,
  • Alberto Pesci,
  • Felice Achilli

DOI
https://doi.org/10.1016/j.rmcr.2016.11.011
Journal volume & issue
Vol. 20, no. C
pp. 59 – 60

Abstract

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We present a case of a 36-year-old woman who developed a severe form of Idiopathic Pulmonary Arterial Hypertension (IPAH) during pregnancy and after emergency delivery. The management of IPAH during or after pregnancy is complex. Due to the severity of her IPAH, an upfront triple combination therapy, including i.v. epoprostenol, was started. The rapid institution of this treatment regimen allowed a complete right ventricular reverse remodelling after 1 year of therapy, leading to a down-titration until complete suspension of epoprostenol from the treatment regimen.

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