A Randomized Controlled Trial of Interleukin-1 Receptor
Antagonist in a Rabbit Model of Ascending Infection in Pregnancy

Robert S. McDuffie; Jill K. Davies; Kimberly K. Leslie; Scott Lee; Michael P. Sherman; Ronald S. Gibbs

doi:10.1155/S1064744901000382

Infectious Diseases in Obstetrics and Gynecology (Jan 2001)

A Randomized Controlled Trial of Interleukin-1 Receptor Antagonist in a Rabbit Model of Ascending Infection in Pregnancy

Robert S. McDuffie,
Jill K. Davies,
Kimberly K. Leslie,
Scott Lee,
Michael P. Sherman,
Ronald S. Gibbs

Affiliations

Robert S. McDuffie: Department of Obstetrics and Gynecology, Kaiser Permanente, 2045 Franklin Street, Denver, CO 80205, USA
Jill K. Davies: University of Colorado Health Sciences Center, Denver, CO, USA
Kimberly K. Leslie: University of Colorado Health Sciences Center, Denver, CO, USA
Scott Lee: University of Colorado Health Sciences Center, Denver, CO, USA
Michael P. Sherman: Department of Pediatrics, University of California-Davis, Davis, CA, USA
Ronald S. Gibbs: University of Colorado Health Sciences Center, Denver, CO, USA

DOI: https://doi.org/10.1155/S1064744901000382
Journal volume & issue: Vol. 9, no. 4
pp. 233 – 237

Abstract

Read online

Objective: To determinewhether treatment with interleukin-1 receptor antagonist (IL1-ra) would affect amniotic fluid concentrations of tumor necrosis factor alpha (TNF-α) and prostaglandins or clinical or microbiological outcomes in a model of ascending bacterial infection in pregnancy.

Published in Infectious Diseases in Obstetrics and Gynecology

ISSN: 1064-7449 (Print); 1098-0997 (Online)
Publisher: Wiley
Country of publisher: United Kingdom
LCC subjects: Medicine: Gynecology and obstetrics; Medicine: Internal medicine: Infectious and parasitic diseases
Website: https://onlinelibrary.wiley.com/journal/7281

About the journal