Sellar B lymphoblastic lymphoma mimics pituitary apoplexy with newly discovered gene mutations in TP53 and PAX5: A case report

Yi Wang; Yajun Yang; Qiuxia Wang; Ce Wang; Xinjuan Xu; Dongao Wang; Feirong Bai; Panpan Li; Xintao Huang

doi:10.3389/fonc.2023.1087232

Frontiers in Oncology (Feb 2023)

Sellar B lymphoblastic lymphoma mimics pituitary apoplexy with newly discovered gene mutations in TP53 and PAX5: A case report

Yi Wang,
Yajun Yang,
Qiuxia Wang,
Ce Wang,
Xinjuan Xu,
Dongao Wang,
Feirong Bai,
Panpan Li,
Xintao Huang

Affiliations

Yi Wang: Department of Neurosurgery, First Hospital of Shanxi Medical University; and The First School of Clinical Medicine, Shanxi Medical University, Taiyuan, Shanxi, China
Yajun Yang: Department of Neurosurgery, First Hospital of Shanxi Medical University; and The First School of Clinical Medicine, Shanxi Medical University, Taiyuan, Shanxi, China
Qiuxia Wang: Department of Gastroenterology, Affiliated Hospital of Southwest Medical University, Luzhou, Sichuan, China
Ce Wang: Department of Neurosurgery, First Hospital of Shanxi Medical University; and The First School of Clinical Medicine, Shanxi Medical University, Taiyuan, Shanxi, China
Xinjuan Xu: Department of Neurosurgery, Shanxi Cardiovascular Disease Hospital, Taiyuan, Shanxi, China
Dongao Wang: Department of Neurosurgery, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China
Feirong Bai: Department of Neurosurgery, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China
Panpan Li: Department of Neurosurgery, First Hospital of Shanxi Medical University; and The First School of Clinical Medicine, Shanxi Medical University, Taiyuan, Shanxi, China
Xintao Huang: Department of Neurosurgery, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, China

DOI: https://doi.org/10.3389/fonc.2023.1087232
Journal volume & issue: Vol. 13

Abstract

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Lymphoblastic lymphoma (LBL) is a rare tumor that accounts for approximately 2-4% of all non-Hodgkin lymphomas, and less than 20% of LBLs are derived from B cells. B- Lymphoblastic lymphoma (B-LBL) often presents as bone marrow and peripheral blood lesions, and is very rare to present as a seller mass. We report a case of sellar B lymphoblastic lymphoma mimicking pituitary apoplexy, and review its diagnosis and treatment process, combined with the literature to deepen the understanding of sellar tumors.

Published in Frontiers in Oncology

ISSN: 2234-943X (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.frontiersin.org/journals/oncology/

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