Characterization of morphological and immunohistochemical prognostic factors in gastrointestinal stromal tumors

Abstract

It carried out a study of a cross-sectional descriptive of patients diagnosed with gastrointestinal stromal tumor. The study population consisted of six patients who underwent excisional biopsy in 2011 at "Arnaldo Milian Castro" Clinical Surgical Hospital of the City of Santa Clara, Villa Clara province. The samples were processed in the Department of Pathology of the same institution, through morphological and immunohistochemical methods, the diagnosis of gastrointestinal stromal tumors were offered. Tumor size, location and the mitotic index, which showed that 57.1% behaved as high risk: To characterize the morphological and immunohistochemical prognostic factors in these tumors and predict their biological behavior of the macro and microscopic morphological parameters were determined. Mienttinen prognostic and Lasota classification was used and immunohistochemistry showed positive to CD117 in 100% of cases, the Ki67 proliferative activity was low at 42.1% of the tumors. The evaluation of the biological behavior of the tumor in patients diagnosed with gastrointestinal stromal tumor in the hospital, according to the index Mienttinen and Lasota, was considered high risk in 57% of patients studied.

Keywords

• tumores del estroma gastrointestinal
• histología