Polish Journal of Pathology (Feb 2017)

Dysgerminoma and gonadoblastoma in the course of Swyer syndrome

  • Tomasz Milewicz,
  • Sandra Mrozińska,
  • Wojciech Szczepański,
  • Magdalena Białas,
  • Marta Kiałka,
  • Katarzyna Doroszewska,
  • Monika Kabzińska-Turek,
  • Andrzej Wojtyś,
  • Artur Ludwin,
  • Łukasz Chmura

DOI
https://doi.org/10.5114/pjp.2016.65876
Journal volume & issue
Vol. 67, no. 4
pp. 411 – 414

Abstract

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We present a case of a woman with primary amenorrhea. Ultrasound imaging showed a uterus of normal size but bands of connective tissues at the site of ovaries. A genetic test was done which revealed the XY karyotype. Swyer syndrome was diagnosed. The patient did not report for the follow-up visits. Three years later, the woman reported back because of increasing abdominal circumference. The patient underwent an operation. Radical hysterectomy was performed. Histopathological examination showed dysgerminoma and gonadoblastoma on the left gonad and dysgerminoma on the right one. This case report presents the natural history of Swyer syndrome.

Keywords