Intrinsic Proteolytic Activities from Cancer Cells Are Sufficient to Activate Alkoxyamine Prodrugs and Induce Cell Death

• Marion Filliâtre,
• Seda Seren,
• Ange W. Embo-Ibouanga,
• Jean-Patrick Joly,
• Véronique Bouchaud,
• Ines Kelkoul,
• Sylvain R. A. Marque,
• Gérard Audran,
• Pierre Voisin,
• Philippe Mellet

Affiliations

Marion Filliâtre

Aix-Marseille University, CNRS, UMR 7273, Marseille, France

Seda Seren

Magnetic Resonance of Biological Systems, UMR 5536 CNRS-University of Bordeaux, Bordeaux, France

Ange W. Embo-Ibouanga

Aix-Marseille University, CNRS, UMR 7273, Marseille, France

Jean-Patrick Joly

Aix-Marseille University, CNRS, UMR 7273, Marseille, France

Véronique Bouchaud

Magnetic Resonance of Biological Systems, UMR 5536 CNRS-University of Bordeaux, Bordeaux, France

Ines Kelkoul

Magnetic Resonance of Biological Systems, UMR 5536 CNRS-University of Bordeaux, Bordeaux, France

Sylvain R. A. Marque

Aix-Marseille University, CNRS, UMR 7273, Marseille, France

Gérard Audran

Aix-Marseille University, CNRS, UMR 7273, Marseille, France

Pierre Voisin

Magnetic Resonance of Biological Systems, UMR 5536 CNRS-University of Bordeaux, Bordeaux, France

Philippe Mellet

Magnetic Resonance of Biological Systems, UMR 5536 CNRS-University of Bordeaux, Bordeaux, France