Clinical and Molecular Characteristics of Megakaryocytes in Myelodysplastic Syndrome

Fangxiu Luo; Jialu Zhao; Yubao Chen; Zhenping Peng; Ran An; Yeling Lu; Jiaming Li

doi:10.1055/s-0044-1787752

Global Medical Genetics (Jun 2024)

Clinical and Molecular Characteristics of Megakaryocytes in Myelodysplastic Syndrome

Fangxiu Luo,
Jialu Zhao,
Yubao Chen,
Zhenping Peng,
Ran An,
Yeling Lu,
Jiaming Li

Affiliations

Fangxiu Luo: Department of Pathology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Jialu Zhao: Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Yubao Chen: Department of Hematology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Zhenping Peng: Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Ran An: Department of Hematology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Yeling Lu: Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
Jiaming Li: Department of Laboratory Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

DOI: https://doi.org/10.1055/s-0044-1787752
Journal volume & issue: Vol. 11, no. 02
pp. 187 – 195

Abstract

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Objective Myelodysplastic syndrome (MDS) is a malignant clonal disorder of hematopoietic stem cells which is characterized by morphologic dysplasia. However, the pathological characteristics of megakaryocytes (MKs) in MDS patients with gene mutation are not well established.

Published in Global Medical Genetics

ISSN: 2699-9404 (Online)
Publisher: Georg Thieme Verlag KG
Country of publisher: Germany
LCC subjects: Science: Biology (General): Genetics; Medicine: Internal medicine: Neoplasms. Tumors. Oncology. Including cancer and carcinogens
Website: https://www.thieme.com/books-main/genetics/product/5705-global-medical-genetics

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Abstract

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