Castelman´s disease of the neck: a case report and literature review

Abstract

Castleman’s disease is a rare pathology, poorly understood. It is considered as a lymphoproliferative disorder, described for the first time in 1954, which may be confused with other causes of lymphadenopathy. We report in this paper the case of a young women presenting with left latero-cervical lymphadenopathy. All the investigations were negative except a large high-vascularized level II cervical lymphadenopathy. We performed a cervicotomy. The extemporaneous histological exam was non-contributive. We decided to perform a complete level II and III left cervical lymphadenectomy. The diagnosis of unicentric Castleman´s disease was confirmed based on the final histological study of the specimen, and the absence other cervical and extra-cervical lymphadenopathy. The patient is free of recurrence at the time of reporting this article.

Keywords

• castleman´s disease
• lymphadenopathy
• surgery