Pengaruh Lama Pemakaian Kontrasepsi Depomedroxyprogesteron Asetat Terhadap Kadar LDL dan HDL

Abstract

Injection contraception is one of the popular contraceptive methods, widely used by KB acceptors (40,88%). Second place is pill contraception (28,48%). Depo Medroxyprogesteron Acetate (DMPA) is one of the injectable contraceptives that is widely used kb acceptor. DMPA has several side effects include changes in serum lipid metabolism in the long-term use. This study aims to the effect of the duration of the use depo medroxyprogesterone acetate on the levels of LDL and HDL. The study was conducted in Lubuk Buaya Public Health and Laboratory of Biochemistry, Faculty of Medicine, University of Andalas Padang in September 2016 to January 2017. Type of study was observational using cross sectional design. Samples numbered 32 people, consisting of two groups of depo medroxyprogesterone acetate acceptor > 3 years, depo medroxyprogesterone acetate acceptors < 3 years. This samples was taken using consecutive sampling technique. Blood was collected from the subject of research by intravenous and measured by Colorimetric Enzymatic Method (CHOD-PAP) for LDL and HDL. The average LDL in two groups study was 93.29 ± 22.83 mg/dl, 90.51 ± 18.22 mg/dl. The average HDL in the two groups study was 70,04 ± 16,4 mg/dl, 65,98 ± 9,7 mg/dl.

Keywords

• low density lipoprotein
• hight density lipoprotein
• dmpa