Preperimetric glaucoma

Abstract

Recently, much literature data is available on the issue of diagnosis of preperimetric glaucoma (PPG), but no recognized algorithms of detecting primary open-angle glaucoma (POAG) at this stage have been developed, and there is no general opinion as to what parameters and techniques should be used. The review offers a generalization of the literature data on PPG diagnosing and specifies the main parameters that should be taken into account in testing POAG patients at the early preperimetric stage. As is known, the diagnosis of glaucoma is based on detectable changes in the optic nerve head and visual field, but the onset of the disease occurs long before the above changes. Currently, the approach shifts towards early OCT diagnosis of glaucoma. Cohort studies show that structural disorders are detected 5–12 years earlier than functional ones in 17–60 % patients with POAG.

Keywords

• preperimetric glaucoma
• optical coherence tomography
• perimetry
• retinal ganglion cell complex
• retinal nerve fiber layer
• internal plexiform layer