Nature Communications (Jan 2023)
Comparative analysis of genome-scale, base-resolution DNA methylation profiles across 580 animal species
- Johanna Klughammer,
- Daria Romanovskaia,
- Amelie Nemc,
- Annika Posautz,
- Charlotte A. Seid,
- Linda C. Schuster,
- Melissa C. Keinath,
- Juan Sebastian Lugo Ramos,
- Lindsay Kosack,
- Ann Evankow,
- Dieter Printz,
- Stefanie Kirchberger,
- Bekir Ergüner,
- Paul Datlinger,
- Nikolaus Fortelny,
- Christian Schmidl,
- Matthias Farlik,
- Kaja Skjærven,
- Andreas Bergthaler,
- Miriam Liedvogel,
- Denise Thaller,
- Pamela A. Burger,
- Marcela Hermann,
- Martin Distel,
- Daniel L. Distel,
- Anna Kübber-Heiss,
- Christoph Bock
Affiliations
- Johanna Klughammer
- CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
- Daria Romanovskaia
- CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
- Amelie Nemc
- CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
- Annika Posautz
- Research Institute of Wildlife Ecology, University of Veterinary Medicine Vienna
- Charlotte A. Seid
- Ocean Genome Legacy Center, Northeastern University Marine Science Center
- Linda C. Schuster
- CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
- Melissa C. Keinath
- Department of Biology, University of Kentucky
- Juan Sebastian Lugo Ramos
- Max Planck Research Group Behavioral Genomics, Max Planck Institute for Evolutionary Biology
- Lindsay Kosack
- CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
- Ann Evankow
- Ocean Genome Legacy Center, Northeastern University Marine Science Center
- Dieter Printz
- Children’s Cancer Research Institute, St. Anna Kinderkrebsforschung
- Stefanie Kirchberger
- Children’s Cancer Research Institute, St. Anna Kinderkrebsforschung
- Bekir Ergüner
- CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
- Paul Datlinger
- CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
- Nikolaus Fortelny
- CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
- Christian Schmidl
- CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
- Matthias Farlik
- CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
- Kaja Skjærven
- Institute of Marine Research (IMR)
- Andreas Bergthaler
- CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
- Miriam Liedvogel
- Max Planck Research Group Behavioral Genomics, Max Planck Institute for Evolutionary Biology
- Denise Thaller
- Department for Pathobiology, University of Veterinary Medicine Vienna
- Pamela A. Burger
- Research Institute of Wildlife Ecology, University of Veterinary Medicine Vienna
- Marcela Hermann
- Medical University of Vienna, Department of Medical Biochemistry
- Martin Distel
- Children’s Cancer Research Institute, St. Anna Kinderkrebsforschung
- Daniel L. Distel
- Ocean Genome Legacy Center, Northeastern University Marine Science Center
- Anna Kübber-Heiss
- Research Institute of Wildlife Ecology, University of Veterinary Medicine Vienna
- Christoph Bock
- CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences
- DOI
- https://doi.org/10.1038/s41467-022-34828-y
- Journal volume & issue
-
Vol. 14,
no. 1
pp. 1 – 23
Abstract
DNA methylation is involved in regulatory processes throughout the animal kingdom. Here, the authors map DNA methylation in 535 vertebrates and 45 invertebrates, establishing a reference dataset for cross-species analysis and exploring epigenetic variation across vertebrate evolution.
