Communications Biology (Aug 2022)

An automated liquid jet for fluorescence dosimetry and microsecond radiolytic labeling of proteins

  • Matthew Rosi,
  • Brandon Russell,
  • Line G. Kristensen,
  • Erik R. Farquhar,
  • Rohit Jain,
  • Donald Abel,
  • Michael Sullivan,
  • Shawn M. Costello,
  • Maria Agustina Dominguez-Martin,
  • Yan Chen,
  • Susan Marqusee,
  • Christopher J. Petzold,
  • Cheryl A. Kerfeld,
  • Daniel P. DePonte,
  • Farid Farahmand,
  • Sayan Gupta,
  • Corie Y. Ralston

DOI
https://doi.org/10.1038/s42003-022-03775-1
Journal volume & issue
Vol. 5, no. 1
pp. 1 – 10

Abstract

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A high-speed liquid jet delivery system improves the X-ray footprinting and mass spectrometry method to label proteins for structural studies.