Nature Communications (Aug 2019)

Chromatin loops associated with active genes and heterochromatin shape rice genome architecture for transcriptional regulation

  • Lun Zhao,
  • Shuangqi Wang,
  • Zhilin Cao,
  • Weizhi Ouyang,
  • Qing Zhang,
  • Liang Xie,
  • Ruiqin Zheng,
  • Minrong Guo,
  • Meng Ma,
  • Zhe Hu,
  • Wing-Kin Sung,
  • Qifa Zhang,
  • Guoliang Li,
  • Xingwang Li

DOI
https://doi.org/10.1038/s41467-019-11535-9
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 13

Abstract

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Three-dimensional genome organization and its effect on transcription remain elusive in rice. Here, the authors map promoter–promoter interactions and heterochromatin interactions using ChIA-PET and reveal spatial correlation between the genetic regulation of eQTLs and e-traits.