Van Tıp Dergisi (May 2020)

Evaluation of Orbital Blood Flow in Age-Related Macular Degeneration by Color Doppler Ultrasonography

  • Mine Karahan,
  • Deniz Kilic,
  • Mehmet Emin Dursun,
  • Birgül Dursun,
  • Aslı Uğurlu,
  • Sedat Ava,
  • Seyfettin Erdem,
  • Ugur Keklikci,
  • Yıldırım Bayezit Sakalar

DOI
https://doi.org/10.5505/vtd.2020.45656
Journal volume & issue
Vol. 27, no. 2
pp. 177 – 183

Abstract

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INTRODUCTION: The aim was to evaluate the ocular blood flow in patients with age-related macular degeneration (AMD) using Doppler-ultrasonography (DUSG). METHODS: This study included the AMD patients from Ophthalmology Department of Dicle University Medical Faculty. Visual acuity, intraocular pressure, anterior and posterior segment examination were performed. The mean peak-systolic-velocity (PSV), enddiastolic-velocity (EDV), resistivity-index (RI) values of the posterior ciliary artery (PSA), central retinal artery (CRA) and ophthalmic artery (OA) were measured with DUSG. RESULTS: There were 39 patients over 50 years of age. Of 39 patients, 15 (%38.46) were female and 24 (%61.54) were male. The mean age was 72.2 +- 8.3 years. There was no statistically significant difference in PSV, EDV and RI values between the eyes with and without AMD (p>0.05). In 11 patients AMD was unilateral. There was no statistically significant difference between the eyes in those patients in terms of mean PSV, EDV and RI values of OA, SRA and PCA (p>0.05). There was a statistically significant difference between the mean RI values of PCA and SRA in cases with neovascular-AMD and nonneovascular-AMD (p<0.05). A statistically significant difference was found between the mean EDV and PSV values of PCA with eyes in patients with HT and in patients without HT (p<0.05). DISCUSSION AND CONCLUSION: The increase in vascular resistance and the decrease in orbital blood flow was shown by DUSG in patients with neovascular-AMD. However, further studies are required to obtain a place for DUSG to detect orbital blood flow disorder in patients with AMD.

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