Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta (Jun 2020)

CLINICAL CASE OF CHRONIC PULMONARY ASPERGILLOSIS IN PATIENT WITH DRUG-RESISTANT PULMONARY TUBERCULOSIS

  • Demidik S. N.,
  • Mashinskaya A. N.,
  • Volf S. B.,
  • Alekso E. N.,
  • Sanukevich T. G.,
  • Vitman N. Z.

DOI
https://doi.org/10.25298/2221-8785-2020-18-3-315-320
Journal volume & issue
Vol. 18, no. 3
pp. 315 – 320

Abstract

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Chronic pulmonary aspergillosis (CPA) is a disease which is diffcult to diagnose and which complicates other respiratory diseases. Forms of CPA include chronic cavitary pulmonary aspergillosis, chronic fbrosing pulmonary aspergillosis, simple aspergilloma, Aspergillus nodules. The presented clinical study demonstrates the diffculties of diagnosis of CPA in a patient with drug-resistant pulmonary tuberculosis and with concomitant respiratory diseases: COPD and bullous emphysema. The early diagnosis of this disease requires computed tomography of chest organs and high-quality methods to confrm aspergillosis: PCR, detection of IgG antibodies or precipitins to Aspergillus in blood, galactomannan into bronchoalveolar lavage. The given clinical case has to draw attention of phthisiologists, pulmonologists, radiologists to chronic pulmonary aspergillosis.

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