Clinical Case Reports (May 2023)

Left ventricular thrombus in a patient with recurrent ischemic stroke events—The role of echocardiography

  • Vasiliki Vanesa Stylianou,
  • Vasiliki Tsampasian,
  • Marios Pavlou,
  • Panagiota Georgiou,
  • Dimitrios Patestos,
  • Lorentzos Kapetis,
  • Vassilios S. Vassiliou,
  • Christos Eftychiou,
  • Michalis Tsielepis,
  • George Bazoukis

DOI
https://doi.org/10.1002/ccr3.7300
Journal volume & issue
Vol. 11, no. 5
pp. n/a – n/a

Abstract

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Key Clinical Message Cardiac ultrasound is recommended in investigating ischemic stroke events. There is increasing evidence that direct oral anticoagulants can be safely used instead of vitamin K antagonists in the setting of left ventricular thrombus. Abstract Cardioembolic stroke is responsible for an increasing number of ischemic strokes. Compared to other causes of stroke, cardioembolic strokes affect a larger brain area. Left ventricular (LV) thrombi account for up to 10% of cardioembolic strokes. It is essential to identify patients at high risk of LV thrombus formation, such as patients with a history of myocardial infarction, patients with reduced ejection fraction, or patients with cardiomyopathies. We present a patient with an ischemic stroke, and the cardiac ultrasound revealed a reduced ejection fraction and the presence of LV thrombus at the apex. The patient had no prior history of cardiovascular diseases. Even in a resource‐limited setting, cardiac ultrasound is recommended to investigate stroke or transient ischemic attack events, especially in patients with a prior history of myocardial infarction. Although patients with LV thrombus should be treated with oral anticoagulants for at least 3 months, the role of direct oral anticoagulants and the optimal period of anticoagulation in this setting needs further investigation.

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