BMC Bioinformatics (Sep 2018)

Prototyping a precision oncology 3.0 rapid learning platform

  • Connor Sweetnam,
  • Simone Mocellin,
  • Michael Krauthammer,
  • Nathaniel Knopf,
  • Robert Baertsch,
  • Jeff Shrager

DOI
https://doi.org/10.1186/s12859-018-2374-0
Journal volume & issue
Vol. 19, no. 1
pp. 1 – 19

Abstract

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Abstract Background We describe a prototype implementation of a platform that could underlie a Precision Oncology Rapid Learning system. Results We describe the prototype platform, and examine some important issues and details. In the Appendix we provide a complete walk-through of the prototype platform. Conclusions The design choices made in this implementation rest upon ten constitutive hypotheses, which, taken together, define a particular view of how a rapid learning medical platform might be defined, organized, and implemented.

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