Role of biobanks in the study of population immunity

Abstract

Review focuses on estimation of population immunity and effectiveness of vaccination against socially significant influenza infection. Long-term observations of the population immunity, including post-vaccine seroprevalence to influenza are an important component of surveillance. The possibility of use of systems of biological banks (biobanks) in these investigations is of great interest. The data on the principles of biobanks design in the world, the scope of their application, the present state of the industry are described. The information about collections of infectious diseases agents is presented. Suggestions to build a network of biobanks in the Russian Federation and its implementation in the system of epidemiological influenza surveillance are formed. The biobanks filling by samples, principles of selection of donors biological specimens, methods of laboratory research are discussed.

Keywords

• population immunity
• vaccine effectiveness
• biobank
• system of storage of biological samples