Nature Communications (Nov 2021)
Age-seroprevalence curves for the multi-strain structure of influenza A virus
- Dao Nguyen Vinh,
- Nguyen Thi Duy Nhat,
- Erwin de Bruin,
- Nguyen Ha Thao Vy,
- Tran Thi Nhu Thao,
- Huynh Thi Phuong,
- Pham Hong Anh,
- Stacy Todd,
- Tran Minh Quan,
- Nguyen Thi Le Thanh,
- Nguyen Thi Nam Lien,
- Nguyen Thi Hong Ha,
- Tran Thi Kim Hong,
- Pham Quang Thai,
- Marc Choisy,
- Tran Dang Nguyen,
- Cameron P. Simmons,
- Guy E. Thwaites,
- Hannah E. Clapham,
- Nguyen Van Vinh Chau,
- Marion Koopmans,
- Maciej F. Boni
Affiliations
- Dao Nguyen Vinh
- Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme
- Nguyen Thi Duy Nhat
- Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme
- Erwin de Bruin
- Department of Viroscience, Erasmus Medical Centre
- Nguyen Ha Thao Vy
- Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme
- Tran Thi Nhu Thao
- Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme
- Huynh Thi Phuong
- Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme
- Pham Hong Anh
- Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme
- Stacy Todd
- Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme
- Tran Minh Quan
- Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme
- Nguyen Thi Le Thanh
- Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme
- Nguyen Thi Nam Lien
- Hue Provincial Hospital
- Nguyen Thi Hong Ha
- Khanh Hoa Provincial Hospital
- Tran Thi Kim Hong
- Dak Lak General Hospital
- Pham Quang Thai
- National Institute of Hygiene and Epidemiology
- Marc Choisy
- Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme
- Tran Dang Nguyen
- Center for Infectious Disease Dynamics, Department of Biology, Pennsylvania State University
- Cameron P. Simmons
- Institute of Vector Borne Disease, Monash University
- Guy E. Thwaites
- Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme
- Hannah E. Clapham
- Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme
- Nguyen Van Vinh Chau
- Hospital for Tropical Diseases
- Marion Koopmans
- Department of Viroscience, Erasmus Medical Centre
- Maciej F. Boni
- Oxford University Clinical Research Unit, Wellcome Trust Major Overseas Programme
- DOI
- https://doi.org/10.1038/s41467-021-26948-8
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 9
Abstract
Multi-strain pathogens, such as influenza, present challenges for interpretation of seroprevalence data as estimates may vary by strain. Here, the authors develop a method for estimating age-specific seroprevalence based on principal components analysis and apply it to influenza data from Vietnam.