Systematic Literature Review of Role of Noroviruses in Sporadic Gastroenteritis

Abstract

We conducted a systematic review of studies that used reverse transcription–PCR to diagnose norovirus (NoV) infections in patients with mild or moderate (outpatient) and severe (hospitalized) diarrhea. NoVs accounted for 12% (95% confidence interval [CI] 10%–15%) of severe gastroenteritis cases among children 95% of the deaths from diarrhea occur.

Keywords

• norovirus
• Norwalk virus
• calicivirus infections
• burden of illness
• diarrhea
• gastroenteritis